
Advanced Cannabis Science: The Other Cannabinoids
Of the approximately 420 chemical compounds found in the cannabis plant, more than 80 cannabinoids have been identified. Much is known about THC, and, more recently, the healing properties of the non-psychotropic CBD have excited much interest, but there’s much more to be discovered in the other cannabinoids produced by the plant.
Cannabigerol (CBG)
Cannabigerol is often referred to as the mother molecule. As the primary biosynthetic precursor of THC, CBD and CBC (cannabichromene), CBG is the stem cell of cannabinoids. Only found in trace amounts in the plant, CBG has not been particularly well studied since its discovery and isolation.
However, researchers have already found an intriguing number of medical uses.
Compared to the greatly psychoactive THC, CBG only binds slightly to the CB1 receptors spread across much of the top area of the brain—roughly with the same affinity as CBD. It also appears to interact with the CB2 receptors of the body and immune system, but whether it functions as an agonist or antagonist is still unclear.
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