Atherosclerosis is a complex inflammatory disease that plays a significant role in the development of heart disease and stroke. In the United States, heart disease is the leading cause of death and claims more lives than cancer. We typically think heart disease and stroke can hit without warning; actually, these diseases develop gradually over time.

Atherosclerosis is characterized by progressive deposition of atherosclerotic plaques (immune cells laden with oxidized low-density lipoproteins/Ox-LDL) followed by the narrowing of blood vessels (arteries) and impaired blood supply to vital organs, such as the heart and brain. Subsequently, inflammation in the intimal regions of the arteries occurs as a result of uncontrolled immunological injury and formation of free radicals. Sedentary lifestyle and bad dietary habits can worsen the disease. The existing treatments are moderately effective, albeit with side effects.

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