A preliminary rat study out of the University of Buffalo’s Research Institute on Addictions (RIA) points to the possibility that certain components in marijuana might be helpful in treating chronic stress-related depression.

The study, published in The Journal of Neuroscience, focused primarily on endocannabinoids — chemicals in the brain that are quite similar to the chemicals known as cannabinoids in marijuana. Endocannabinoids are involved in appetite, memory, mood, and pain sensations. They’re also involved in the psychoactive effects that cannabis has on us, as well as brain functions like cognition, behavior, and emotions.

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