The nondescript four-story former tenement at 149 Bowery, with its ground floor “Organic Spa and Shop” sandwiched between lighting fixture outlet stores, is an unlikely staging ground for the next push in the battle against the prohibition of marijuana.

Yet its third floor tenant, Marley Natural, is on the vanguard of a growing movement of “potrepreneurs” that activists and market analysts alike think could be the troops that will lead the legalization movement to victory in their decades-long struggle to decriminalize cannabis consumption in the U.S.

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